The pore of activated 20S proteasomes has an ordered 7-fold symmetric conformation
نویسندگان
چکیده
منابع مشابه
The pore of activated 20S proteasomes has an ordered 7-fold symmetric conformation.
The 20S proteasome is a large multisubunit assembly that performs most of the intracellular non-lysosomal proteolysis of eukaryotes. Substrates access the proteasome active sites, which are sequestered in the interior of the barrel-shaped structure, through pores that are opened by binding of activator complexes. The crystal structure of yeast proteasome in complex with an 11S activator suggest...
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ژورنال
عنوان ژورنال: The EMBO Journal
سال: 2003
ISSN: 1460-2075
DOI: 10.1093/emboj/cdg436